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Groups reported improved physical functioning and less fatigue (mainly testosterone but also estradiol, which in ruminants is also anabolic and is produced in relatively large quantities). Bodybuilder during 1 year of self-administration of testosterone and anabolic glycoside Yes Yes Glipizide Glyburide Insulin Metformin Pioglitazone Antidiabetic agents Yes Yes Carbamazepine Phenobarbital Phenytoin Rifampin CYP3A4 enzyme inducers Yes Yes Azithromycin Erythromycin Ketoconazole CYP3A4 enzyme inhibitors Yes Yes Aspirin Ibuprofen Meloxicam Naproxen NSAIDs Yes Yes.

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